منابع مشابه
Epigenetic control of the immune system: histone demethylation as a target for drug discovery.
In recent years significant progress has been made in our understanding of epigenetic control of a wide range of cellular processes. This has come about both through the concerted effort of the research community and through the development of technologies essential to the area. The importance of the epigenetic control of the immune system is becoming increasingly clear, and therefore epigeneti...
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During the past two decades, scientific interest and public health concern have shifted their focus from issues connected with overt clinical lead disease to the detection of subtle clinical and biochemical abberations.' This has brought about a change in the thinking on the health risks that are associated with lead toxicity.23 Although major emphasis has been set on lead hazards among pediatr...
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Recently, interest has centered on the immune system as a target organ for toxic effects. This seems a reasonable choice, since it can be argued that alterations induced in this system as a result of a toxic insult could lead to impaired immunity. Such an alteration may be manifest in altered disease susceptibility. Documenting toxic effects upon the immune system is a difficult task due to the...
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Resistance to commonly used malaria drugs is spreading and new drugs are required urgently. The recent identification of a relict chloroplast (apicoplast) in malaria and related parasites offers numerous new targets for drug therapy using well-characterized compounds. The apicoplast contains a range of metabolic pathways and housekeeping processes that differ radically to those of the host ther...
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ژورنال
عنوان ژورنال: Immunology and Immunogenetics Insights
سال: 2013
ISSN: 1178-6345,1178-6345
DOI: 10.4137/iii.s12145